@article{jiang2012origami,
  abstract = {Although a multitude of promising anti-cancer drugs have been developed over the past 50 years, effective delivery of the drugs to diseased cells remains a challenge. Recently, nanoparticles have been used as drug delivery vehicles due to their high delivery efficiencies and the possibility to circumvent cellular drug resistance. However, the lack of biocompatibility and inability to engineer spatially addressable surfaces for multi-functional activity remains an obstacle to their widespread use. Here we present a novel drug carrier system based on self-assembled, spatially addressable DNA origami nanostructures that confronts these limitations. Doxorubicin, a well-known anti-cancer drug, was non-covalently attached to DNA origami nanostructures through intercalation. A high level of drug loading efficiency was achieved, and the complex exhibited prominent cytotoxicity not only to regular human breast adenocarcinoma cancer cells (MCF 7), but more importantly to doxorubicin-resistant cancer cells, inducing a remarkable reversal of phenotype resistance. With the DNA origami drug delivery vehicles, the cellular internalization of doxorubicin was increased, which contributed to the significant enhancement of cell-killing activity to doxorubicin-resistant MCF 7 cells. Presumably, the activity of doxorubicin-loaded DNA origami inhibits lysosomal acidification, resulting in cellular redistribution of the drug to action sites. Our results suggest that DNA origami has immense potential as an efficient, biocompatible drug carrier and delivery vehicle in the treatment of cancer.},
  author = {Jiang, Q and Song, C and Nangreave, J and Liu, XW and Lin, L and Qiu, DL and Wang, ZG and Zou, GZ and Liang, XJ and Yan, H and Ding, BQ},
  interhash = {9e764e96d61b049a0f22322807aae36e},
  intrahash = {4489634919a85c9e368260c61d44ce24},
  journal = {JOURNAL OF THE AMERICAN CHEMICAL SOCIETY},
  month = {8},
  number = 32,
  title = {DNA Origami as a Carrier for Circumvention of Drug Resistance},
  uniqueid = {000307487200044|edswsc},
  volume = 134,
  year = 2012
}

@incollection{Pest,
  author = {Dinges, Martin},
  booktitle = {Das Europäische Gesundheitssystem. Gemeinsamkeiten und Unterschiede in historischer Perspektive},
  editor = {Eckart, Wolfgang U. and Jütte, Robert},
  interhash = {c960e1e2832d097662b7516b17eba4e9},
  intrahash = {43db4377c13fd77c695f9d48a93ba15e},
  pages = {19-51},
  series = {Medizin, Gesellschaft und Geschichte 3},
  title = {Nord-Süd Gefälle in der Pestbekämpfung. Italien Deutschland und England im Vergleich},
  year = 1994
}

@inproceedings{Cai:2011:LTD:1935826.1935920,
  abstract = {Social tagging recommendation is an urgent and useful enabling technology for Web 2.0. In this paper, we present a systematic study of low-order tensor decomposition approach that are specifically targeted at the very sparse data problem in tagging recommendation problem. Low-order polynomials have low functional complexity, are uniquely capable of enhancing statistics and also avoids over-fitting than traditional tensor decompositions such as Tucker and Parafac decompositions. We perform extensive experiments on several datasets and compared with 6 existing methods. Experimental results demonstrate that our approach outperforms existing approaches.},
  acmid = {1935920},
  address = {New York, NY, USA},
  author = {Cai, Yuanzhe and Zhang, Miao and Luo, Dijun and Ding, Chris and Chakravarthy, Sharma},
  booktitle = {Proceedings of the fourth ACM international conference on Web search and data mining},
  doi = {10.1145/1935826.1935920},
  interhash = {414f80ad09d994af6f448446c04cd226},
  intrahash = {52a9e5fd121bf7be4fa8670cc93a7197},
  isbn = {978-1-4503-0493-1},
  location = {Hong Kong, China},
  numpages = {10},
  pages = {695--704},
  publisher = {ACM},
  series = {WSDM '11},
  title = {Low-order tensor decompositions for social tagging recommendation},
  url = {http://doi.acm.org/10.1145/1935826.1935920},
  year = 2011
}

@inproceedings{conf/cikm/DingFJPCPRDS04,
  author = {Ding, Li and Finin, Timothy W. and Joshi, Anupam and Pan, Rong and Cost, R. Scott and Peng, Yun and Reddivari, Pavan and Doshi, Vishal and Sachs, Joel},
  booktitle = {CIKM},
  ee = {http://doi.acm.org/10.1145/1031289},
  interhash = {17031c743c455bf9de56e142d727dbb7},
  intrahash = {ab5c85d78daba236ca1bb5ad49865ee5},
  pages = {652-659},
  title = {Swoogle: a search and metadata engine for the semantic web.},
  url = {http://dblp.uni-trier.de/db/conf/cikm/cikm2004.html#DingFJPCPRDS04},
  year = 2004
}

@inproceedings{DBLP:conf/semweb/DingPFJPK05,
  author = {Ding, Li and Pan, Rong and Finin, Timothy W. and Joshi, Anupam and Peng, Yun and Kolari, Pranam},
  bibsource = {DBLP, http://dblp.uni-trier.de},
  booktitle = {International Semantic Web Conference},
  crossref = {DBLP:conf/semweb/2005},
  ee = {http://dx.doi.org/10.1007/11574620_14},
  interhash = {fbd1c77889dc928ae2c157761d1b5567},
  intrahash = {12ca34d21f87f455fe38ca90c5ddf377},
  pages = {156-170},
  title = {Finding and Ranking Knowledge on the Semantic Web.},
  url = {http://ebiquity.umbc.edu/get/a/publication/197.pdf},
  year = 2005
}

@inproceedings{conf/cikm/DingFJPCPRDS04,
  author = {Ding, Li and Finin, Timothy W. and Joshi, Anupam and Pan, Rong and Cost, R. Scott and Peng, Yun and Reddivari, Pavan and Doshi, Vishal and Sachs, Joel},
  booktitle = {CIKM},
  ee = {http://doi.acm.org/10.1145/1031289},
  interhash = {17031c743c455bf9de56e142d727dbb7},
  intrahash = {ab5c85d78daba236ca1bb5ad49865ee5},
  pages = {652-659},
  title = {Swoogle: a search and metadata engine for the semantic web.},
  url = {http://dblp.uni-trier.de/db/conf/cikm/cikm2004.html#DingFJPCPRDS04},
  year = 2004
}